During an episode of transient global amnesia, a person is unable to create new memory, so the memory of recent events. This confused state isn't caused by a more common neurological condition, such as epilepsy or stroke. We have found that depression, previous head injury and family history of dementia may predict TGA recurrence.ĭementia Diffusion-weighted imaging Recurrent Risk factors Transient global amnesia. Transient global amnesia is an episode of confusion that comes on suddenly in a person who is otherwise alert. DWI lesions were observed in 24 patients and were located anywhere within the hippocampus.ĭWI lesions were not significantly associated with outcomes (recurrence, subjective memory impairment, dementia). Of 15 patients with confirmed recurrent TGA, two developed dementia and four subjective memory impairment. recurrent, 15.4% vs 46.7%, p = 0.01) and family history of dementia (isolated vs. Risk factors associated with recurrence were head injury (isolated vs. Eighty-four patients had possible comorbidities or risk factors for TGA, though no single risk factor was ubiquitous. Cortical spreading depression (CSD) was proposed as a possible cause decades ago. The prevalence of stressful events before a TGA attack makes it hard to overlook these precipitating factors, given that stress has the potential to organically effect the brain. Fifteen of 93 (16%) patients experienced a recurrence of TGA.Īmong precipitating events, physical activities inducing Valsalva-like manoeuvres were most common, followed by emotional stress. Transient global amnesia (TGA) is a benign memory disorder with etiologies that have been debated for a long time. Patients were followed from 2004 to 2016. We evaluated clinical history, family history and magnetic resonance diffusion-weighted imaging (DWI) studies of 93 prospective patients with TGA. We attempted to determine risk factors for TGA, as well as prognostic factors that may cause recurrence. Aetiology of transient global amnesia (TGA) remains uncertain, though many have been proposed, including ischaemic, migrainous or epileptic pathologies.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |